Ligands, Receptors, and Transcription Factors that Mediate Inter-Cellular and Intra-Cellular Communication during Ovarian Follicle Development

Angiogenic factors and ovarian follicle development

Ovarian follicles require an adequate blood supply for oxygen, nutrients and hormones, in addition to eliminating CO2 and other metabolites. Acquisition of an adequate vascular supply is probably a limiting step in the selection and maturation of the dominant follicle. In this way, there is a progressive interest in the study of the growth factors involved in the angiogenic process. In addition...

An Efficient Algorithm to Inter and Intra-Cell Layout Problems in Cellular Manufacturing Systems with Stochastic Demands

Cellular and molecular aspects of ovarian follicle ageing.

It is well established that age-related decline of the biological capacity of a woman to reproduce is primarily related to the poor developmental potential of her gametes. This renders female ageing the most significant determinant of success in IVF. Starting with a reference picture of the main molecular and cellular failures of aged oocytes, granulosa cells and follicular microenvironment, th...

Linear Channel Modeling and Error Analysis for Intra/Inter-Cellular Ca2+ Molecular Communication.

The use of intra/inter-cellular calcium ion (Ca2+) signaling for molecular communication (MC) is investigated in this paper. In particular, the elevation of the intracellular Ca2+ concentration upon the external excitation, i.e., Ca2+ wave generation, and the intercellular propagation of Ca2+ wave over consecutive cells are studied for information transmission. The main objective of this paper ...

Combining Intra- and Inter-cellular Dynamics to Investigate Intestinal Homeostasis

This paper reports on the multi-scale modelling of an intestinal crypt cellular structure coupled with Wnt signalling. Using formal modelling techniques based on the stochastic π-calculus, which supports ambients needed for compartments, we develop a collection of cell and molecular level models. The focus of our study is the role of Wnt in the control of cell division and differentiation. Usin...